Saturday, 31 October 2009

Oradol




Oradol may be available in the countries listed below.


Ingredient matches for Oradol



Domiphen Bromide

Domiphen Bromide is reported as an ingredient of Oradol in the following countries:


  • Japan

Ketorolac

Ketorolac is reported as an ingredient of Oradol in the following countries:


  • Bangladesh

Ketorolac tromethamine (a derivative of Ketorolac) is reported as an ingredient of Oradol in the following countries:


  • Bangladesh

International Drug Name Search

Tuesday, 27 October 2009

Amoxiclav Sandoz




Amoxiclav Sandoz may be available in the countries listed below.


Ingredient matches for Amoxiclav Sandoz



Amoxicillin

Amoxicillin trihydrate (a derivative of Amoxicillin) is reported as an ingredient of Amoxiclav Sandoz in the following countries:


  • Belgium

  • Luxembourg

Clavulanate

Clavulanic Acid potassium (a derivative of Clavulanic Acid) is reported as an ingredient of Amoxiclav Sandoz in the following countries:


  • Belgium

  • Luxembourg

International Drug Name Search

Thursday, 22 October 2009

Dicyclomine



Pronunciation: dye-SYE-kloe-meen
Generic Name: Dicyclomine
Brand Name: Bentyl


Dicyclomine is used for:

Treating symptoms of irritable bowel syndrome. It may also be used for other conditions as determined by your doctor.


Dicyclomine is an anticholinergic. It works by blocking a chemical in the smooth muscle of the stomach and intestines, causing them to relax, which reduces cramping.


Do NOT use Dicyclomine if:


  • you are allergic to any ingredient in Dicyclomine

  • you have blockage of the esophagus, stomach, intestine, or urinary tract

  • you have heart problems due to severe bleeding

  • you have glaucoma

  • you have inflammation of the esophagus due to acid reflux, loss of strength in the intestinal muscles, or chronic inflammation and ulceration of the bowel

  • you have myasthenia gravis (a condition in which the muscles become progressively paralyzed)

  • you are breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.



Before using Dicyclomine:


Some medical conditions may interact with Dicyclomine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have chronic inflammation or ulcers of the bowel, diarrhea, enlargement of the prostate, hiatal hernia, kidney or liver disease, a nervous system disease, overactive thyroid, or urinary blockage or retention

  • if you have heart disease, heart failure, a history of rapid heartbeat, or high blood pressure

  • if you are at risk for glaucoma

Some MEDICINES MAY INTERACT with Dicyclomine. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amantadine, antiarrhythmics (eg, quinidine), antihistamines (eg, diphenhydramine), benzodiazepines (eg, diazepam), monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), narcotic pain medicine (eg, meperidine), nitrates (eg, nitroglycerin, isosorbide), nitrites (eg, sodium nitrite), phenothiazines (eg, chlorpromazine), sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Dicyclomine's side effects

  • Metoclopramide or phenothiazines (eg, chlorpromazine) because their effectiveness may be decreased by Dicyclomine

  • Digoxin because the risk of its side effects may be increased by Dicyclomine

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dicyclomine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Dicyclomine:


Use Dicyclomine as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Dicyclomine is usually given as an injection at your doctors office, hospital, or clinic. If you will be using Dicyclomine at home, a health care provider will teach you how to use it. Be sure you understand how to use Dicyclomine. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Dicyclomine is for intramuscular (IM) injection only. It is NOT for intravenous (IV) use.

  • Do not use Dicyclomine if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • The injection form of Dicyclomine is only given short-term when the oral form cannot be taken. Your health care provider will prescribe the oral form of Dicyclomine as soon as you are able to take it.

  • Use Dicyclomine on a regular schedule around the clock, unless your doctor tells you otherwise.

  • If you miss a dose of Dicyclomine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dicyclomine.



Important safety information:


  • Dicyclomine may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Dicyclomine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Dicyclomine; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Dicyclomine may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.

  • Dicyclomine may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

  • Use Dicyclomine with caution in the ELDERLY; they may be more sensitive to its effects.

  • Dicyclomine should not be used in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dicyclomine while you are pregnant. Dicyclomine is found in breast milk. Do not breast-feed while taking Dicyclomine.


Possible side effects of Dicyclomine:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; constipation; decreased sweating; difficulty sleeping; dizziness; drowsiness; dry mouth; headache; lightheadedness; loss of taste; nausea; nervousness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; confusion; diarrhea; difficulty focusing your eyes; difficulty moving; difficulty speaking; difficulty urinating; disorientation; exaggerated sense of well-being; fainting; hallucinations; pounding in the chest; rapid heartbeat; short-term memory loss; unusual weakness; vomiting.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Dicyclomine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; convulsions (seizures); difficulty breathing; dilated pupils; disorientation; excessive thirst; flushed, hot, dry skin; hallucinations or unusual behavior; muscle weakness; nausea; rapid heartbeat and breathing; restlessness; unusual dizziness or drowsiness; unusually dry mouth; vomiting.


Proper storage of Dicyclomine:

Store Dicyclomine at room temperature, below 86 degrees F (30 degrees C). Protect from freezing. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dicyclomine out of the reach of children and away from pets.


General information:


  • If you have any questions about Dicyclomine, please talk with your doctor, pharmacist, or other health care provider.

  • Dicyclomine is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dicyclomine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dicyclomine resources


  • Dicyclomine Side Effects (in more detail)
  • Dicyclomine Use in Pregnancy & Breastfeeding
  • Drug Images
  • Dicyclomine Drug Interactions
  • Dicyclomine Support Group
  • 23 Reviews for Dicyclomine - Add your own review/rating


  • Dicyclomine Prescribing Information (FDA)

  • dicyclomine Concise Consumer Information (Cerner Multum)

  • Bentyl Monograph (AHFS DI)

  • Bentyl Prescribing Information (FDA)



Compare Dicyclomine with other medications


  • Colitis
  • Irritable Bowel Syndrome

Monday, 12 October 2009

Tarmin




Tarmin may be available in the countries listed below.


Ingredient matches for Tarmin



Loperamide

Loperamide hydrochloride (a derivative of Loperamide) is reported as an ingredient of Tarmin in the following countries:


  • Mexico

International Drug Name Search

Wednesday, 7 October 2009

Revlimid



Generic Name: lenalidomide (Oral route)

len-a-LID-oh-mide

Oral route(Capsule)

Lenalidomide may cause human birth defects, hematological toxicity (neutropenia and thrombocytopenia), deep vein thrombosis (DVT), and pulmonary embolism (PE). Lenalidomide is an analogue of thalidomide, a known human teratogen that causes severe life-threatening human birth defects. If taken during pregnancy, lenalidomide may cause birth defects or death to an unborn baby. Avoid pregnancy due to potential toxicity and to avoid fetal exposure. Lenalidomide is only available under a special restricted distribution program called RevAssist(R). Lenalidomide is associated with significant neutropenia and thrombocytopenia in patients with del 5q myelodysplastic syndromes. CBC should be monitored weekly for the first 8 weeks of therapy and at least monthly thereafter. Patients may require dose interruption and/or reduction and the use of blood product support and/or growth factors. There is an increased risk of DVT and PE in patients with multiple myeloma who receive lenalidomide. Observe patients for signs and symptoms of thromboembolism .



Commonly used brand name(s)

In the U.S.


  • Revlimid

Available Dosage Forms:


  • Capsule

Therapeutic Class: Immune Modulator


Uses For Revlimid


Lenalidomide is used to treat anemia (low red blood cells) in patients with a certain type of myelodysplastic syndrome (MDS) called 5q MDS. Patients with this type of MDS may have very low red blood cell counts and require blood transfusions.


Lenalidomide is also used in combination with dexamathasone to treat multiple myeloma (plasma cell cancer) in patients who have received at least one prior therapy.


This medicine is available only under a special restricted distribution program called RevAssist® program.


Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, lenalidomide is used in certain patients with the following medical condition:


  • Multiple myeloma, first-line treatment, in combination with dexamethasone (treatment of bone marrow cancer; used together with dexamethasone).

Before Using Revlimid


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of lenalidomide in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of lenalidomide in the elderly.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersXStudies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Digoxin

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Neutropenia (low white blood cells) or

  • Thrombocytopenia (low platelets)—Use with caution. May make these conditions worse.

  • Infection—May decrease your ability to fight infections.

  • Kidney disease, severe—May increase the amount of lenalidomide in your body and increase the risk of side effects.

  • Liver disease—Use caution as studies have not been done.

  • Multiple myeloma—May increase your risk for serious side effects.

Proper Use of Revlimid


Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not stop taking this medicine without checking with your doctor first.


It is very important that you understand the requirements of the RevAssist® program, and become familiar with the RevAssist® educational materials and Patient Medication Guide. Direct any questions to your doctor or pharmacist before starting lenalidomide therapy. .


You should take the necessary precautions to avoid pregnancy while taking lenalidomide. Use one highly effective form of birth control plus an additional effective form of birth control at the same time, if abstinence is not the chosen method. Begin this 4 weeks before starting lenalidomide and continue it for 4 weeks after stopping the medication.


There is a telephone survey and patient registry that you must participate in while taking lenalidomide. Ask your doctor or pharmacist if you have any questions about what you need to do.


Swallow the capsule whole, do not break, chew, or open it.


It is important that you have blood tests at regular intervals. Keep all appointments with your doctor for the tests.


It is important that you have pregnancy tests at regular intervals.


Male patients, even those who have had a vasectomy, must use a latex condom during sexual contact with a female patient.


Male patients: Do not donate semen or sperm while taking lenalidomide.


Do not donate blood while taking lenalidomide.


You should not share this medication with anyone, even if someone else has similar symptoms.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (capsules):
    • For anemia in patients with myelodysplastic syndrome:
      • Adults—10 milligrams (mg) once a day, taken with water. Your doctor may adjust your dose if needed.

      • Children—Use and dose must be determined by your doctor.


    • For multiple myeloma:
      • Adults—25 milligrams (mg) once a day, taken with water. This medicine may be taken together with dexamethasone. Your doctor may adjust your dose as needed.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using Revlimid


It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to allow for a change in the dose. Blood tests may be needed to check for any unwanted effects.


Your doctor will want to see you every 4 weeks for pregnancy tests if you have a regular menstrual cycle, and every 2 weeks if you have an irregular cycle.


Call your doctor or 1-888-688-2528 for emergency contraception information if you think you are pregnant or, for males, if you think that your sexual partner may be pregnant.


Seek medical attention if you develop any shortness of breath, chest pain, or arm or leg swelling.


Do not breastfeed while you are using this medicine.


This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.


Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin; red skin lesions; severe acne or skin rash; sores or ulcers on the skin; or fever or chills while you are using this medicine.


Lenalidomide may cause a serious type of reaction called tumor lysis syndrome. Your doctor may give you a medicine to help prevent this. Call your doctor right away if you have a decrease or change in urine amount; joint pain, stiffness, or swelling; lower back, side, or stomach pain; a rapid weight gain; swelling of the feet or lower legs; or unusual tiredness or weakness.


Revlimid Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Black, tarry stools

  • bleeding gums

  • blood in the urine or stools

  • chest pain

  • chills

  • convulsions

  • cough

  • decreased urine

  • difficult or labored breathing

  • dry mouth

  • fever

  • increased thirst

  • irregular heartbeat

  • loss of appetite

  • lower back or side pain

  • mood changes

  • muscle pain or cramps

  • nausea or vomiting

  • numbness or tingling in the hands, feet, or lips

  • painful or difficult urination

  • pale skin

  • pinpoint red spots on the skin

  • shortness of breath

  • sore throat

  • sores, ulcers, or white spots on the lips or in the mouth

  • swollen glands

  • tightness in the chest

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • wheezing

Incidence not known
  • Anxiety

  • dizziness or lightheadedness

  • fainting

  • fast heartbeat

  • pain, redness, or swelling in the arm or leg

  • sudden shortness of breath or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Abnormal or decreased touch sensation

  • back pain

  • bloody nose

  • blurred vision

  • body aches or pain

  • bruising

  • burning while urinating

  • burning, numbness, tingling, or painful sensations

  • change in taste

  • constipation

  • contusion

  • cough-producing mucus

  • depressed mood

  • diarrhea

  • difficulty having a bowel movement (stool)

  • difficulty with moving

  • discouragement

  • drowsiness

  • dry skin and hair

  • dryness or soreness of the throat

  • ear congestion

  • fast, slow, irregular, pounding, or racing heartbeat or pulse

  • feeling sad or empty

  • feeling unusually cold

  • flushing, redness of the skin

  • hair loss

  • headache

  • hoarseness or husky voice

  • irritability

  • itching skin

  • itching, pain, redness, swelling, tenderness, or warmth on the skin

  • lack or loss of strength

  • large, flat, blue or purplish patches in the skin

  • loose stools

  • loss of appetite

  • loss of interest or pleasure

  • loss of taste

  • loss of voice

  • muscle aching

  • muscle spasms, stiffness, or twitching

  • nasal congestion

  • nervousness

  • night sweats

  • pain

  • pain in the arms or legs

  • pain in joints

  • pain or tenderness around the eyes and cheekbones

  • pounding in the ears

  • rash

  • runny nose

  • seizures

  • shivering

  • sleeplessness

  • sneezing

  • stomach pain

  • stuffy or runny nose

  • sweating increased

  • swelling of the hands, ankles, feet, or lower legs

  • swollen joints

  • tender, swollen glands in the neck

  • tiredness

  • trembling

  • trouble with concentrating

  • trouble with sleeping

  • trouble with swallowing

  • troubled breathing with exertion

  • unable to sleep

  • unsteadiness or awkwardness

  • unusually warm skin

  • upper abdomen or stomach pain

  • voice changes

  • vomiting

  • weakness in the arms, hands, legs, or feet

  • weight gain

  • weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Revlimid side effects (in more detail)



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More Revlimid resources


  • Revlimid Side Effects (in more detail)
  • Revlimid Use in Pregnancy & Breastfeeding
  • Revlimid Drug Interactions
  • Revlimid Support Group
  • 1 Review for Revlimid - Add your own review/rating


  • Revlimid Prescribing Information (FDA)

  • Revlimid Consumer Overview

  • Revlimid Monograph (AHFS DI)

  • Revlimid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lenalidomide Professional Patient Advice (Wolters Kluwer)



Compare Revlimid with other medications


  • Anemia
  • Multiple Myeloma