Tuesday, 1 December 2009

Dextromethorphan/Phenylephrine Syrup


Pronunciation: DEX-troe-meth-OR-fan/FEN-il-EF-rin/DYE-fen-HYE-dra-meen
Generic Name: Dextromethorphan/Phenylephrine
Brand Name: Triaminic Cold and Cough Day/Night Club Pack


Dextromethorphan/Phenylephrine Syrup is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, itchy nose or throat, itchy or watery eyes, cough due to colds, upper respiratory infections, or allergies. It may also be used for other conditions as determined by your doctor.


Dextromethorphan/Phenylephrine Syrup is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.


Do NOT use Dextromethorphan/Phenylephrine Syrup if:


  • you are allergic to any ingredient in Dextromethorphan/Phenylephrine Syrup

  • you have severe or uncontrolled high blood pressure, severe heart blood vessel disease, fast heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you are taking droxidopa or sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Dextromethorphan/Phenylephrine Syrup:


Some medical conditions may interact with Dextromethorphan/Phenylephrine Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems (eg, fast, slow, or irregular heartbeat; heart disease), high or low blood pressure, low blood volume, diabetes, blood vessel problems, a stroke, the blood disease porphyria, glaucoma or increased pressure in the eye, thyroid problems, or trouble sleeping

  • if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea), or chronic cough, or if your cough occurs with large amounts of mucus

  • if you have a history of stomach or bowel ulcers; a blockage of your stomach, bladder, or bowel; kidney problems; trouble urinating; or an enlarged prostate or other prostate problems

  • if you take medicine for high blood pressure

Some MEDICINES MAY INTERACT with Dextromethorphan/Phenylephrine Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased

  • Abiraterone, catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, linezolid, MAOIs (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Dextromethorphan/Phenylephrine Syrup's side effects

  • Beta-blockers (eg, propranolol), bromocriptine, or hydantoins (eg, phenytoin) because their side effects may be increased by Dextromethorphan/Phenylephrine Syrup

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Dextromethorphan/Phenylephrine Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Dextromethorphan/Phenylephrine Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Dextromethorphan/Phenylephrine Syrup:


Use Dextromethorphan/Phenylephrine Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Dextromethorphan/Phenylephrine Syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • This product contains 2 different syrups, 1 for the morning and 1 for the evening. Be sure you understand how to take Dextromethorphan/Phenylephrine Syrup. Check with your doctor or pharmacist if you are not sure which syrup to take in the morning and which to take in the evening.

  • If you miss a dose of Dextromethorphan/Phenylephrine Syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Dextromethorphan/Phenylephrine Syrup.



Important safety information:


  • Dextromethorphan/Phenylephrine Syrup may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Dextromethorphan/Phenylephrine Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol while you are taking Dextromethorphan/Phenylephrine Syrup.

  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Dextromethorphan/Phenylephrine Syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do not take diet or appetite control medicines while you are taking Dextromethorphan/Phenylephrine Syrup without checking with your doctor.

  • Dextromethorphan/Phenylephrine Syrup has a decongestant, antihistamine, and cough suppressant in it. Before you start any new medicine, check the label to see if it has a decongestant, antihistamine, and cough suppressant in it too. If if does or if you are not sure, check with your doctor or pharmacist.

  • Check with your doctor before using another medicine that contains diphenhydramine, including one used on the skin.

  • Do not use Dextromethorphan/Phenylephrine Syrup for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.

  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

  • If your symptoms do not improve within 7 days, if they get worse or return, or if they occur along with a fever, check with your doctor.

  • If your cough does not improve within 7 days, if it goes away and comes back, or if it occurs along with a fever, rash, or persistent headache, check with your doctor.

  • Dextromethorphan/Phenylephrine Syrup may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Dextromethorphan/Phenylephrine Syrup. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Dextromethorphan/Phenylephrine Syrup may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Dextromethorphan/Phenylephrine Syrup for a few days before the tests.

  • Tell your doctor or dentist that you take Dextromethorphan/Phenylephrine Syrup before you receive any medical or dental care, emergency care, or surgery.

  • Use Dextromethorphan/Phenylephrine Syrup with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, drowsiness, dizziness, dry mouth, nervousness, sleeplessness, and trouble urinating.

  • Caution is advised when using Dextromethorphan/Phenylephrine Syrup in CHILDREN; they may be more sensitive to its effects, especially excitability.

  • Dextromethorphan/Phenylephrine Syrup should not be used in CHILDREN between 4 and 6 years old without first checking with the child's doctor. It should not be used in children younger than 4 years old. Discuss any questions or concerns with your doctor.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dextromethorphan/Phenylephrine Syrup while you are pregnant. It is not known if Dextromethorphan/Phenylephrine Syrup is found in breast milk. Do not breast-feed while taking Dextromethorphan/Phenylephrine Syrup.


Possible side effects of Dextromethorphan/Phenylephrine Syrup:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Anxiety; constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; loss of coordination; mental or mood changes (eg, depression); nervousness; seizures; severe dizziness, drowsiness, light-headedness, or headache; severe dryness of mouth, nose, and throat; severe or persistent trouble sleeping; shortness of breath; tremor; unusual bruising or bleeding; unusual tiredness or weakness; vision problems (eg, double vision, blurred vision).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; flushing; hallucinations; mental or mood changes; muscle spasms; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; trouble breathing; unusually fast, slow, or irregular heartbeat; vomiting.


Proper storage of Dextromethorphan/Phenylephrine Syrup:

Store Dextromethorphan/Phenylephrine Syrup at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dextromethorphan/Phenylephrine Syrup out of the reach of children and away from pets.


General information:


  • If you have any questions about Dextromethorphan/Phenylephrine Syrup, please talk with your doctor, pharmacist, or other health care provider.

  • Dextromethorphan/Phenylephrine Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Dextromethorphan/Phenylephrine Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Dextromethorphan/Phenylephrine resources


  • Dextromethorphan/Phenylephrine Use in Pregnancy & Breastfeeding
  • Dextromethorphan/Phenylephrine Drug Interactions
  • Dextromethorphan/Phenylephrine Support Group
  • 0 Reviews for Dextromethorphan/Phenylephrine - Add your own review/rating


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